在线国产一区二区_成人黄色片在线观看_国产成人免费_日韩精品免费在线视频_亚洲精品美女久久_欧美一级免费在线观看

  Home>News Center>Life
         
 

US researchers find two chemicals to fight HIV
(Xinhua)
Updated: 2005-03-06 14:56

Two chemical compounds may help the immune systems of HIV-infected people fight the disease without invasive gene therapy, US scientists reported Saturday.

The new research, presented at the 2005 Palm Springs Symposium on HIV/AIDS, was conducted by researchers at the University of California, Los Angeles(UCLA) AIDS Institute. It demonstrates that the new chemicals activate telomerase, a protein that boosts immune cells' ability to divide, enabling them to continue destroying HIV-infected cells, the researchers said.

"The immune cells that fight HIV naturally produce telomerase during the infection's early phase, but stop once HIV becomes a chronic condition," explained Rita Effros, a professor at UCLA medical school who led the study. "The two compounds switched telomerase back on in the cells."

Earlier research by the UCLA team has showed that inserting thetelomerase gene into the immune cells of an HIV-infected person prevented the cells from aging prematurely. The telomerase enabledthe immune cells to divide indefinitely, stimulated their production of a viral-fighting molecule and prolonged their power to kill HIV-infected cells.

In this study, the scientists isolated immune cells from the blood of HIV-infected persons and cultured the cells with the chemical compounds. They were surprised to see that the compounds produced the same three changes in the cells as those created by the gene therapy.

"We discovered we didn't need to use gene therapy to reactivatethe telomerase and strengthen the immune system's capacity to stave off HIV," said Effros, who is also a member of the UCLA AIDSInstitute. "We were thrilled to see we could create the same changes in the cells without relying on an invasive procedure."

But the researchers did not point out the components of the chemicals, partly because the study was sponsored by Geron, a bio-pharmaceutical firm that also provided the compounds.

Immune cells that battle HIV must constantly divide in order to continue performing their protective functions. The massive amount of division prematurely shortens these cells' ends, or telomeres, ultimately exhausting the immune system.

Previous research showed that telomerase rejuvenates the telomeres and allows the immune cells to remain youthful and active as they replicate under HIV's attack. Drugs that activate telomerase also offer therapeutic potential for a wide spectrum ofdegenerative diseases and chronic conditions in which cellular aging plays a role.

"I'm really excited by our findings. This progress moves us onestep closer to drugs that work by switching telomerase on permanently and keeping the immune cells young and strong in theirfight against infection," Eros said. "These therapies are also easier to develop than gene-therapy drugs."



Cecilia Cheung in a commercial
Green light for 'Amber'
Bill Gates bestowed knighthood
  Today's Top News     Top Life News
 

FM calls for US, N.Korea flexibility in nuclear talks

 

   
 

Wen lowers 2005 economic growth target

 

   
 

Hu's vision for cross-Straits ties hailed

 

   
 

Agricultural tax to be scrapped from 2006

 

   
 

Dollar decline won't lead to forex sale

 

   
 

Liu Xiang wants more time and privacy

 

   
  A face for one thousand hands
   
  The secret to man's aggression: in his finger?
   
  Accuser's family praises Jackson in video
   
  US draws jeers for abortion comments at UN
   
  Brazilian, 125, may be the oldest woman
   
  You're a pain, but let's get married anyway
   
 
  Go to Another Section  
 
 
  Story Tools  
   
  Feature  
  Chen Ning Yang, 82, to marry a 28-year-old woman  
Advertisement
         
主站蜘蛛池模板: 天天干网站 | 一级特黄视频 | 欧美三级欧美一级 | 女人高潮特级毛片 | 成人免费毛片片v | 亚洲综合区 | 激情久久综合 | 欧美日韩四区 | 国产不卡在线视频 | 99国产精品99久久久久久粉嫩 | 亚洲天堂国产 | 成年女人毛片 | 午夜av网站 | 亚洲天堂一区二区三区 | 一级毛片免费看 | 欧美三级三级三级爽爽爽 | 国产理论在线观看 | 亚洲最大网站 | 国产精品国产精品国产专区不卡 | 国产精品毛片一区二区在线看 | 97福利视频 | 久久国产一区二区三区 | 成人av免费看 | 久久网页 | 欧美日韩黄 | 欧美一区二区在线观看 | 911精品国产一区二区在线 | 91亚洲精品乱码久久久久久蜜桃 | 五月伊人网 | 午夜久久精品 | 久久成人在线 | 国产日韩欧美日韩大片 | 午夜影院免费观看 | 亚洲一区二区三区免费视频 | 黄色在线免费看 | 欧美91视频 | 国产不卡在线视频 | 午夜免费小视频 | 日韩精品在线一区二区 | 五月婷婷六月丁香 | 日本一本在线 |